Keep at room temperature from moisture and warmth. Usually do not freeze. Monitor your medication. You need to be mindful if any one is employing it improperly or without a prescription.

When employed for an prolonged time, this medication might not work also and could need distinctive dosing. Talk with your medical doctor if this medication stops Performing effectively.

If another person has overdosed and it has severe signs or symptoms including passing out or difficulty respiratory, contact 911. If not, contact a poison Regulate Middle at once.

The mixture of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric individuals under 6 yrs of age, mainly because the combination may possibly result in deadly respiratory despair With this age inhabitants.

Get emergency professional medical assist When you've got hives; tricky respiration; swelling within your face, lips, tongue, or throat. signs of an allergic reaction:

Utilize other supportive actions (including oxygen and vasopressors) while in the administration of circulatory shock and pulmonary edema as indicated. Cardiac arrest or arrhythmias would require advanced daily life-aid methods. Gastric emptying could possibly be helpful in eliminating unabsorbed drug.

No evidence of tumorigenicity was noticed in male and female mice at codeine dietary doses approximately 400 mg/kg/working day (somewhere around reminiscent of forty five instances the MRHD with a mg/m2 basis).

The causal purpose of opioids during the clinical syndrome of hypogonadism is mysterious since the several professional medical, Actual physical, lifestyle, and psychological stressors that will impact gonadal hormone degrees haven't been sufficiently controlled for in reports click here carried out thus far [see ADVERSE REACTIONS (6)].

Normally use an accurate milliliter (mL) measuring machine to measure the right degree of PROMETHAZINE WITH CODEINE ORAL Option. Do not utilize a house teaspoon to evaluate your medicine. It's possible you'll accidentally acquire excessive. You can question your pharmacist with the measuring unit it is best to use and the way to measure the correct dose. Respiration problems (respiratory depression)that can cause Demise and opioid withdrawal can happen if you start taking or cease getting other medicines though having PROMETHAZINE WITH CODEINE ORAL SOLUTION, which includes: selected antibiotics

Psychological dependence, physical dependence, and tolerance may well build on repeated administration of opioids; as a result, Promethazine with Codeine Oral Answer need to be prescribed and administered to the shortest period which is consistent with specific patient treatment method goals and sufferers should be reevaluated just before refills [see Dosage and Administration (two.

Get clinical assist instantly for those who notice any of the next: sluggish/shallow breathing, severe drowsiness/problem waking up, confusion.

Animal replica experiments haven't been carried out with the drug combination-promethazine and codeine. It isn't known whether this drug mix can result in fetal harm when administered to your Expecting female or can have an affect on copy capacity.

The diagnostic evaluation of individuals with this syndrome is difficult. In arriving at a diagnosis, it's important to recognize circumstances in which the medical presentation contains the two severe healthcare illness (e.

Inform your medical professional If you're Expecting or Imagine you may be pregnant. Through pregnancy, this product is just not proposed. It may harm an unborn baby. Speak with your health care provider with regard to the hazards and advantages of this medication. See also Warning part.